![4-[6-[4-[(甲氧羰基)氨基]苯基]-4-(4-嗎啉基)-1H-吡唑并[3,4-D]嘧啶-1-基]-1-哌啶羧酸甲酯](http://struc.chem960.com/strucimg/1062200/pxsubsub9avgbptlc32coxnm5aee.png)
4-[6-[4-[(甲氧羰基)氨基]苯基]-4-(4-嗎啉基)-1H-吡唑并[3,4-D]嘧啶-1-基]-1-哌啶羧酸甲酯抑制劑WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than
